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Immune System May Make or Break Cancer
Latest Cancer News
Nov. 19, 2007: Cancer researchers today reported that the body's immune system may be the tipping point toward or away from cancer.
Their findings may help scientists develop new cancer treatments that harness the immune system's cancer-fighting powers. Here's an overview of the studies, published in today's advance online editions of Nature and Proceedings of the National Academy of Sciences.
Startling Findings
In Nature, scientists show that a healthy immune system may hold some cancers in check.
The results may pave the way for the development of new therapies to convert cancer into a controllable chronic disease,
write the researchers. They injected a cancer-causing substance into mice. Some mice developed growing tumors, while other mice developed tumors that stayed small.
But those small, stable tumors started to grow when the scientists suppressed the mice's immune systems.
The bottom line: A healthy immune system helps prevent cancer, though it didn't stop every small tumor from growing.
The researchers included graduate student Catherine Koebel and Robert Schreiber, PhD, of the pathology and immunology department at Washington University School of Medicine in St. Louis.
Their findings are startling
and demonstrate that considering cancer as a fatal disease is not always appropriate,
writes Cornelius Melief, MD, PhD, in a Nature editorial.
Melief works at Leiden University in the Netherlands.